itch.io

You can either use Crossover (https://www.codeweavers.com/crossover) which is a paid product. You should get support for this. You can also use Whiskey (https://getwhisky.app/) which is free but the devs stepped away from this product. You can try wine for older models. I use wine personally but I dont know how well it works for Mac. I Linux game so we have the same issues with playing windows games but since mac is proprietary you won't have as many options. Let us know if you find something that works.