R3M's spellbook injector no longer works, and appears to have been abandoned twice by different modders, so it's unlikely to be updated. Is that going to make all your mods unusable? That would be a real shame.
Hey I think this is an updated version for enchanted: https://www.patreon.com/posts/spellbook-v2-55723766
I haven't tested it yet but hopefully it works :)