Some further comments:
-> Done 5 Meta Reincarnations now. First one was so hard to get that I nearly burnt out on playing the game before I reached it. Second one took about half the time (mostly due to reduced requirements). Third one+, since it only had a "D" coin cost, was able to do it much faster.
-> Meta Reincarnation, doesn't state that you keep your Research.
-> Really feels like you shouldn't have to redo the more tedious content, each time in a meta reincarnation. Like having to unlock pills again, unlocking the clinic, unlocking the organization bank (so you don't lose progress each time and have to use an auto-clicker to get first few properties built), or unlocking the net computer.
-> Research provides upgrades, based on % dedication, not on the amount of money. So if you set it to 100%, when you produce 0 money, it provides research at lightning speeds, costing you nothing.
-> Only unlocking 1 Time point per reincarnation, just means redoing a lot of other tedious gameplay. And as multiple unlocks costs 2+ points, that means a lot of reincarnations are needed.
-> Really feel like time multiplier should be unlocked outside of meta reincarnation. There is so many times before I reached the first meta reincarnation that I felt the game was glacially slow and was ready to quit the game as nothing was happening, at any decent rate.
-> Really frustrating having to redo all the net circuit boards. I end up having no upgrades for hours (as the gear/cards I need are beyond Skynet (11 board) and I get all the early gears) and have to empty the card row constantly, otherwise I get constant reports of no space. Plus, it takes too long to gain new circuit boards and the research for net progress doesn't seem to do anything.
-> Not sure why the game resets my profile picture. I don't lose access to the choice after a meta reincarnation, but have to manually reset the picture each reincarnation.
-> Charisma needs to be retuned. It takes longer to increase it over category specific, revenue increases. And its effect, isn't that strong.
-> I don't like that you can't choose more than one body modification once I've unlocked them at the clinic. I'm fine with paying the karma cost each loop.
-> Haven't unlocked the new story yet, as I've focused on gaining the time multipliers, to speed up my loops. Have the 400% speed boost at the moment, and almost the 500%.