I love this game! However, the alternate settings have a few bugs and quirks that make them very difficult to play.
If you want to do Urban Fantasy or Cyberpunk, there are no alternate card prompts. You have to manually replace "Kingdom" and "throne" and other genre-specific terms, which isn't so bad up until the prompts insist on "wars" and "heirs" and other things that just wouldn't be a thing in modern settings. It's workable, but difficult.
The alternate settings also have some categories pre-filled that should not be pre-filled. They might have been written before the team decided that the cards decided what the characters would be driven by.