I'm not so sure but I'd say it's possible by modifying the save files, but I wouldn't recommend it unless you know what you're doing since the game may break easily. Sadly we can't go back to important choices in routes, it's a pain in the ass but I'd suggest starting over, the game is not that long if you know what you're supposed to do (also, I think that the "break Emma/Katarina" route is buggy since I think it's supposed to start after you fuck Katarina and Mario asks you to seduce Emma but I'm not so sure about it).
My recommendation is to play with your left hand and use the space button to advance the text and the numbers for choices, just using the mouse to travel around the map.