I like the upside+downside combo. It's really fascinating having my favorite go to buff (damage) come with a severe enough downside to actually need to not go crazy with it. With some time spent balancing the options, this could make a really engaging game loop!
Also I love that the 'increase all projectile's size' kinda looks a little like it's only upside until you think about it for an extra second. When I took it and the bullets were near undodgable, I did actually laugh.
Excellent work!