...That didn't answer my question. It looks like you went out of your way to not answer, frankly. A simple yes or no for each one would be sufficient, if you please.
Harem/Sharing is likely(not NTR, but poly potentially elective NTR on some story line). Pregnancy no. Futa/Trans no. Femdom yes.
But the reason I answered like above is that I have most of the story developed but in terms of adult content its all kind of subject to change as the project grows. So I would add that anything is possible just depends where the winds take us.