Oh, I hadn't realized the game was a semi-sequel. I may check it out.
Viewing post in Monstrous Liberation Prologue comments
There really isn't much in the way of narrative overlap - you don't HAVE to play Opportunity to enjoy MonLib by any means (although obviously I think it's good). Sasha just made sense as a protagonist when we were in the early stages of planning for MonLib, so we thought it'd be neat to have that little bit of connective tissue between the games.