I really liked the artstyle, but the gameplay could really use some work.
First of - everzthing but the lasgun felt weak. If there was an obvious cost associated with using it, I couldn't find it while testing. The bullets of regular guns stop at edges of the screen (more on that later) while the las gun seems to kill enemies two mail codes over.
The edges of the screen being inconsistent and messing with aiming really screws with... well, aiming. Or generally playing the game. The way my guy is aiming jumping from point A to whatever-he-wants-to at screen transition was difficult to overcome to say the least.
That sai, I found the best strategy to be to camp the generator room with a lasgun. There is really no complication to get me to move from there, which is a real shame - for example, if I had to defend the specimen in the tank at the spawn room, that would be an entirely different story.
All of that said and done, I liked a lot about this, especially for a gamejam game. The obviously hand drawn sprites do a lot for me, and the sound effects, while far from prefect, do show a genuine understandanging of game design.