A bit expensive; compare to Portable Plan
GameMaker Studio 1-2, but can also export effects to other engines via PNG sequences and GIFs.
"PixFlipBook brings the ability to use Sprite Sheets right into After Effects in the form of a native plugin for maximum efficiency. Each parameter can be fully animated using keyframes, expressions, or both! The generated sprite can then be positioned with an aligned point for additional control over the sprite's location on screen!"
"Designed to eliminate gaps and other artifacts appearing between tiles in unity, but useful for many other things including removing similar artifacts from spritesheets animations"