Project Settings

1. Open Godot and click Project in the top left area of the window
2. Click Project Settings...
3. On the right side of the settings window, turn on Advanced Settings

Window Sizing

1. In the left panel of the settings window, go to Display > Window
2. For Viewport Width and Viewport Height, you want either 320x180 or 640x360
3. For testing I prefer Window Width Override and Window Height Override to be 1280x720 for easy testing. You may use exclusive full screen + your monitor resolution if you want.

320x180 and 640x360 can scale up to common monitor resolutions including 1920x1080, 2560x1440, and 3840x2160 while still being a reasonable size for sprites. This scaling will prevent your pixels from squashing on most full screen monitors.

Here's are the possible resolutions your game can have depending on the viewport size:

Window Stretching

1. Mode should be canvas_items
   
2. Scaling Mode should be integer

Godot recommends viewport mode but it seems to do the same thing as canvas_items but make fonts blurry. Set scale mode to integer if you want your game to be "resizable". This will let you resize the window but create black borders until the window is big enough to hold the next resolution without pixel squashing. If you don't want this, be sure to turn Resizable to Off above.

Rendering Sprites

1.  In the left panel, go to Rendering > Textures
2. Default Texture Filter should be Nearest
   

I also recommend using Aseprite Wizard if you use Aseprite for pixel art. It will allow you to easily export Aseprite files, including animations without having to go through the trouble of labeling the spritesheet. It will also set the texture filter for every sprite you import to linear.

Summary

Now you can start making your pixel art games without having to worry about it looking odd.

• Project > Project Settings...
• Turn on Advanced Settings
• Display > Window > Viewport = 640x360
• Display > Window > Window Override = 1280x720
• Display > Window > Mode = canvas_items
• Display > Window > Scale Mode = integer
• Rendering > Textures > Default Texture Filter = Nearest

Thanks for reading.