The image below is my room. The three sections are the lower level, the upper left then the upper right. The searchable areas are the alleyways, the trashcan and some of the stores. there are two NPCs to interact with.

Here are my three animations. The npc wobbling on the ledge, the player character rail grinding once they can cross the gap, and then a looping anim for the character in the shop.

I created my location to have a distinct style and a feeling of dynamic framing that is sometimes missing in Adventure games. I think the angle might be difficult to work with though.