New & popular paid games with Mouse support tagged 2D

Explore games with Mouse support tagged 2D on itch.io. Uses two-dimensional "sprites", 2D images created and used on a flat plane, as opposed to the three-dimensional models o · Sell your games with Mouse support on itch.io to have them show up here.

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cardTD

A tower defense focused on card combos, mechanical synergies, and a limited tower count

goki_dev

Strategy

Botsfield

$2.50

Rodtyju

Strategy

Play in browser

That's not my Neighbor

$2.99

Work as a doorman in a building infested with doppelgangers.

Simulation

Roll around and squash bugs in this mini rogue-like arcade shooter!

Jesseo

Action

Tanks V5

$5.50

Want to play a tank game that shoot each other? COME PLAY TANKS!

Jay-C

Shooter

GIF

Human Souvenir

$3.99

A toy-like game about taking care of a little human being.

Shaman Garage

Simulation

Ball Clicker 2.5

5€

A new version of ball clicker 2

HTGames

Sternly Worded Adventures

A rogue-like word-puzzle RPG.

Puzzle

Action

Bots of Boria (N-Body Simulator)

-100%

Particle Life Simualtion.

Simulation

Puzzle

A game about a bee in the war

Litygames / PowerPoint Games

Action

Play in browser

Green Squares

Pure Simple Physics Fun. Challenge yourself in a chaotic and colourful time trial!

spooky_stone

StoneChess

A quick strategy game with single- and multiplayer

CMW-Games

Strategy

JettyCat

Blast off like a cat with a jetpack!

and0

Action

Mr Snuggles Dungeon Adventure

A teddy bear alone in a dungeon, his only hope for escape is... kitchen implements?

unklnik

Action

HitoMe

$2.50

Hello Friend

Benjamin

Adventure

Dyztopia: Post-Human RPG

$9.99

It's a game about quitting your job.

Dyzdev

Role Playing

Ages of Conflict: World War Simulator

$6.99

Create a massive Free-For-All across multiple maps with Randomization, Statistics and History tracking

JokuPelle

Simulation

Play in browser

The Return To The Building

A Very Short Horror Game About Returning To Your Old Building.

[+Free Demo] Capture, train and battle beings while learning vocabulary in a procedural RPG world

CodeSpree

Role Playing

TriMatch - A Casual Puzzle Game

$2.99

Match the side of the triangles to score as much points as possible!

Puzzle

$19.99

Simulation

$6.99

Turn based tactical RPG where you are the Undead.

Shattering Pie

Strategy

Cats on Broombas

$15

Puzzling cats!

Eigen Lenk

Puzzle

Shoot & Destroy X

$1.59

Save the Galaxy!

Samuel Sousa

Shooter

The Rangers Run And Survive

Ready for robotic chaos? In The Rangers, you will face endless hordes of enemies that evolve with each wave.

Alien Game Studio

Survival

Fall Of Angels - Remaster

$4.59

LT Brayitan

Adventure

Gibbon: Beyond the Trees

$12.99

A hopeful eco-adventure.

Broken Rules

Adventure

Speed Run!

-100%

Race, Jump, and Dash through 2D Thrills in This Speedy Adventure!

Ahsan Makes Games

Platformer

Hotel Perkkow and the Two Vegetarian Werewolves

Vegetarian werewolves ? How come ?

John Flex

Visual Novel

Haunted Tower: Tower Defense

$3.99

A clever tower defense game about Strategy, not Gems

morion4000

Strategy

Play in browser

⚡️ ProSignal

-100%

SURVIVAL SANDBOX・EARLY ACCES

Survival

$1.99

Card Game

$4.99

Water Festa is a top-down shooter inspired by Thailand's Songkran water festival.

Plataklom

Shooter

Cube Tower Defense 5

The 5th and Final Instalment of the "Cube Tower Defense" saga

GDplague

Strategy

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New & popular paidGamesGamesToolsGame assetsComicsBooksPhysical gamesAlbums & soundtracksGame modsEverything elsewith Mouse support tagged 2D (1,551 results)

New itch.io is now on YouTube!

New & popular paid
Games Tools Game assets Comics Books Physical games Albums & soundtracks Game mods Everything else
with Mouse support tagged 2D (1,551 results)