Hello Jericho! Given that the jam is only 48 hours, I doubt you'd be able to write that much story into the game. But I would consider it if you show me some of your previous work and/or tell me what kind of stories do you enjoy writing.
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The only disadvantage I could imagine with this stack would be that making tons of moving graphics and physics simulations can be difficult to pull off. Depending on this year's theme, we could make an adventure game (think Sierra games or Snatcher by Hideo Kojima) or a strategy game (clicker games, 4X, city builder).
I'm a full-stack developer by profession and have built things for the web for the past 5 years. Here's my GitHub profile. If you're more of a visual person, check out this little interactive website thing I made a while ago.
If you want to join me creating something for the jam, let me know! Artists, and developers – doesn't matter, as long as you're a nice person.