I like the idea of escape rooms! There's so much you can do with them in terms of gameplay, pacing, theme etc. Unfortunately in my first playthrough I found the key and won the game within the first 10 seconds! Maybe I'm Lord Speedrun supreme :)
For escape rooms, you'll want more than the one item. You can create a sequence of events that unlock as you collect each item. Maybe there's some allegory (hidden meaning) in your level that the player must work out. Get creative and have some fun with it, beyond the win condition! A lot of the time it's the experience we're after, not necessarily beating the game