There's no way to set import settings on doodle studio animations, couldn't find a way to extend the compression features from unity into the files. Yeah this is a known limitation and might make it so longer/larger animations require too much memory for mobile targets.
You can convert doodle animations into sprite sheets by Right Click on file > Doodle Studio 95 > Convert To Sprite Sheet (works for multiple files)
The resulting sprite sheet is a regular texture file that'll have full use of unity's compression and texture settings.
Right now there's no automated way of having a Doodle Animator use a sprite sheet instead of a doodle animation file, hopefully I can make that work.
You could have a simple script that replaces the sprites in the renderer from the ones in the sprite sheet, see https://pastebin.com/pRtPQVL3
But yeah, there're also ways to automate any replacing so hit me up before you do any boring work.