I'm enjoying it thus far! The mouse controls could use some work, and I would like to see keyboard or gamepad controls. It's probably more amenable to the d-pad on a game controller rather than the mouse. The mouse doesn't quite feel like a match for this kind of gameplay (although I assume you have to support it so people don't complain).
The knot puzzles seem to have a relatively simple set of rules such that once you figure out what you can't do, it's much easier to sort of unconsciously work your way through a puzzle, even if it's long or seemingly complicated.
There aren't many knot puzzles which I was able to solve "at a distance," and I suppose that means I wasn't spending much of my time conceiving of a grand strategy to solve the whole puzzle and instead relied on not doing what I know you can't do. Once you know what you can't do, you can work through the puzzles by feel.
I'm not really sure what to think of that, since The Witness also has that quality. I mean, the point of it is to figure out the rule, and once you do that, all of the puzzles become much easier.
But maybe you want to start giving people new mechanics or combined mechanics right at the moment most people figure it out, kind of like how Too Many Cooks changes the show just when you think you know where it's going.
I got through all of the knot puzzles. I just started with the twist puzzles. I'll update you on my thoughts as I work through the game. :-)