I think it's interesting how the controls account for both movement and abilities. I think having a combo of w & d attacks to shoot up/down would be cool.
It's a bit tricky though since you generally have to run into enemies in order to use an ability. This may feel weird but maybe try reversing the weaker combos so moving left makes you shoot right etc. then have higher combos force you to move closer to enemies so theres a bit of risk/reward.
Cool concept and well done especially for three hours!