Basically I have a game in mind but I want to do it in 16 bits, so I want to choose a 16 bit console, but I don't know if the game fit it's controller. So I wanted to know if I can use modern controllers on an old video game or if I will need to adapt it.

Mind if I jump on this thread and ask a similar question? Is it ok to work on an already retro game and build it for an older retro console. So for example a Megadrive game designed for Atari 2600 say?