Toptagged Sci-fi and Tower Defense (337 results)
Explore games tagged Sci-fi and Tower Defense on itch.io · Upload your games to itch.io to have them show up here.
New itch.io is now on YouTube!
Subscribe for game recommendations, clips, and more
Take the challenge of surviving waves of increasingly difficult evil mutants! Grab a friend to hunt and slay them.
Shooter
An orbital tower defense game with roguelite elements.
Strategy
Play in browser
When RTS meets Tower Defense in a cartoon style. Fight monstrous mutants to save the Humanity’s fate.
Strategy
Strategy
Explore, Exploit, Exterminate, Expand. Survive in an unknown land inside the gas giant, Jupiter.
Survival
a 2D intense tower defence game made for GBJam 11 packed with action and levels to beat
Strategy
Play in browser
Help defend the world in this cute Tower Defense RPG! Do you have the power to save the tower?
Role Playing
Play in browser
Build your space station, then defend, profit, die, and repeat until the universe collapses.
Strategy
How quickly can you obliterate the crawler menace in this top-down action-strategy hybrid?
Action
Play in browser
Loading more games...