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16 pixels by 16 pixels is a common resolution for assets matching a low-res pixel art aesthetic. Although the assets may not be specifically 16x16, they are designed to work in a graphical setting where objects are around that size.

Pixel Art refers to the charming, simplistic, retro/renaissance style of very-low-resolution graphics, such as from the 1977-1995 Atari, GameBoy, & Super Nintendo (SNES) eras.

Featuring gameplay that moves horizontally across a scrolling background, with characters typically walking, running, or jumping from left to right. Often includes platforming elements and side-view perspectives.

Related to the process of arranging game maps using a set of tile graphics (often call tilesets)

The graphics that make up a tile map

Instructions on how to do something